ACUTE MYELOID LEUKEMIA: FROM BIOLOGY TO CLINICAL PRACTICES THROUGH DEVELOPMENT AND PRE-CLINICAL THERAPEUTICS

Safari Hat Recent studies have provided several insights into acute myeloid leukemia.Studies based on molecular biology have identified eight functional mutations involved in leukemogenesis, including driver and passenger mutations.Insight into Leukemia stem cells (LSCs) and assessment of cell surface markers have enabled characterization of LSCs f

Yuki Ueda,1 Tsuneaki Kenzaka,1,2 Ayako Noda,1 Yu Yamamoto,1 Masami Matsumura1 1Division of General Internal Medicine, Jichi Medical University Hospital, Shimotsuke, 2Division of Community Medicine and Career Development, Kobe University Graduate School of Medicine, Japan Introduction: Kawasaki disease (KD) most commonly develops in infants, althoug